Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042832 | 0.88 | CFTR (0.45) | P2RX7SMN1; SMN2KDM4ECFTRLMNA | |
| SCHEMBL20042755 | 0.86 | GRM5 (0.43) | P2RX7GBA1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL20042839 | 0.86 | P2RX7 (0.45) | P2RX7GBA1CNR1SMN1; SMN2KDM4E | |
| SCHEMBL20042817 | 0.86 | PKM (0.44) | P2RX7GBA1KDM4ELMNAMEN1 | |
| SCHEMBL20042873 | 0.84 | P2RX7 (0.38) | P2RX7GBA1CNR1KDM4ECFTR | |
| SCHEMBL20042872 | 0.84 | P2RX7 (0.44) | P2RX7GBA1CNR1SMN1; SMN2CFTR | |
| SCHEMBL20042685 | 0.84 | HTT (0.42) | P2RX7GBA1SMN1; SMN2 | |
| SCHEMBL20042751 | 0.84 | HSD17B10 (0.49) | P2RX7GBA1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL20042743 | 0.83 | P2RX7 (0.40) | P2RX7GBA1CNR1SMN1; SMN2KDM4E | |
| SCHEMBL20042912 | 0.83 | PROKR1 (0.39) | P2RX7PIK3CDGBA1CNR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |