Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042719 | 0.88 | HSD17B10 (0.46) | HSD11B1MGLLMEN1KMT2ANTSR1 | |
| SCHEMBL20042795 | 0.87 | HPGD (0.46) | HSD11B1PKMNTSR1 | |
| SCHEMBL20042725 | 0.85 | PDE2A (0.41) | MGLLNTSR1GRM5 | |
| SCHEMBL20042771 | 0.85 | P2RX7 (0.47) | ALDH1A1L3MBTL1KDM4EPKMMEN1 | |
| SCHEMBL20042927 | 0.80 | TACR2 (0.40) | ALDH1A1HSD11B1L3MBTL1KDM4EMGLL | |
| SCHEMBL20042668 | 0.74 | HPGD (0.51) | ALDH1A1HSD11B1L3MBTL1KDM4EMEN1 | |
| SCHEMBL20042689 | 0.73 | P2RX7 (0.39) | GRM5 | |
| SCHEMBL20042739 | 0.73 | P2RX7 (0.44) | ALDH1A1HSD11B1L3MBTL1KDM4EMGLL | |
| SCHEMBL20042732 | 0.73 | P2RX7 (0.44) | ALDH1A1HSD11B1L3MBTL1KDM4EMGLL | |
| SCHEMBL20042737 | 0.73 | P2RX7 (0.44) | ALDH1A1HSD11B1L3MBTL1KDM4EMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |