Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042719 | 0.89 | HSD17B10 (0.46) | GPR6HSD11B1PDE10ANTSR1 | |
| SCHEMBL20042722 | 0.87 | ALDH1A1 (0.43) | PKMHSD11B1NTSR1 | |
| SCHEMBL20042886 | 0.84 | HPGD (0.49) | HPGDHTR1APKMGPR6HSD11B1 | |
| SCHEMBL20042725 | 0.82 | PDE2A (0.41) | PDE10ANTSR1 | |
| SCHEMBL20042752 | 0.78 | HPGD (0.47) | HPGDTSHR | |
| SCHEMBL20042887 | 0.77 | GPR6 (0.42) | HPGDGPR6TSHR | |
| SCHEMBL20042789 | 0.77 | GPR6 (0.42) | HPGDGPR6TSHR | |
| SCHEMBL20042803 | 0.76 | GPR6 (0.40) | HPGDGPR6TSHR | |
| SCHEMBL20042792 | 0.76 | TACR3 (0.46) | HPGDGPR6 | |
| SCHEMBL20042667 | 0.76 | TACR3 (0.46) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |