Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 13/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | TACR2 | P21452 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042896 | 0.88 | GRM5 (0.38) | TACR3TACR2TACR1P2RX7HCRTR2 | |
| SCHEMBL20042727 | 0.83 | TACR3 (0.47) | TACR3KCNH2TACR2TACR1P2RX7 | |
| SCHEMBL20042878 | 0.83 | TACR3 (0.47) | TACR3KCNH2TACR2TACR1P2RX7 | |
| SCHEMBL20042900 | 0.83 | TACR3 (0.38) | TACR3KCNH2TACR2TACR1P2RX7 | |
| SCHEMBL20042865 | 0.83 | TACR3 (0.42) | TACR3KCNH2TACR2 | |
| SCHEMBL20042958 | 0.83 | TACR3 (0.42) | TACR3KCNH2TACR2 | |
| SCHEMBL20042742 | 0.82 | PROKR1 (0.35) | TACR3KCNH2TACR2KDM4ESMN1; SMN2 | |
| SCHEMBL20042879 | 0.82 | TACR3 (0.36) | TACR3KCNH2TACR2TACR1 | |
| SCHEMBL20042852 | 0.82 | TACR3 (0.47) | TACR3KCNH2TACR2TACR1P2RX7 | |
| SCHEMBL20042898 | 0.81 | TACR3 (0.45) | TACR3KCNH2KDM4ESMN1; SMN2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |