Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20044064 | 0.94 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL20044071 | 0.91 | ATM (0.51) | SMN1; SMN2MAPTRAB9AL3MBTL1ATM | |
| SCHEMBL20044143 | 0.90 | RAB9A (0.40) | SMN1; SMN2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL20044010 | 0.89 | L3MBTL1 (0.44) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL20044375 | 0.89 | RAB9A (0.40) | SMN1; SMN2ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL22621466 | 0.88 | RAB9A (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL20044480 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL20048548 | 0.85 | MEN1 (0.45) | SMN1; SMN2ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL20044738 | 0.84 | ATM (0.39) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL20044135 | 0.84 | NR4A2 (0.39) | SMN1; SMN2RAB9AKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2022-04-28 | — | — | US | disclosed |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2020-11-05 | — | — | US | disclosed |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | SMN1; SMN2 4288/4885ALDH1A1 1202/4885MAPT 3629/4885 |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | SMN1; SMN2 4288/4885ALDH1A1 1202/4885MAPT 3629/4885 |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | SMN1; SMN2 4288/4885ALDH1A1 1202/4885MAPT 3629/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | SMN1; SMN2 4295/4885ALDH1A1 1182/4885MAPT 3633/4885 |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | SMN1; SMN2 4288/4885ALDH1A1 1202/4885MAPT 3629/4885 |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | SMN1; SMN2 4288/4885ALDH1A1 1202/4885MAPT 3629/4885 |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | SMN1; SMN2 4288/4885ALDH1A1 1202/4885MAPT 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.