SCHEMBL20046972

SCHEMBL20046972

CCCOCCOCCOCCn1cc(C(=O)O)nn1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.41
DPP4 P27487 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GBA1 P04062 1/20 0.39
DRD2 P14416 3/20 0.38
KDM6B O15054 1/20 0.38
KDM5C P41229 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
KDM3A Q9Y4C1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
HCAR3 P49019 1/20 0.35
CHRNA7 P36544 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20047100 0.85 DPP4 (0.46) FABP7DPP4ALDH1A1LMNAKDM6B
SCHEMBL6071691 0.82 L3MBTL1 (0.50) DPP4ALDH1A1LMNAKDM5CL3MBTL1
SCHEMBL20702418 0.81 DPP4 (0.44) DPP4ALDH1A1LMNAKDM6BKDM5C
SCHEMBL22941261 0.80 DRD2 (0.39) FABP7ALDH1A1LMNAGBA1DRD2
SCHEMBL20047063 0.80 MGMT (0.43) FABP7DPP4ALDH1A1LMNADRD2
SCHEMBL6072137 0.80 DPP4 (0.45) DPP4ALDH1A1LMNAGBA1KDM5C
SCHEMBL23173466 0.79 DRD2 (0.38) FABP7ALDH1A1LMNAGBA1DRD2
SCHEMBL23130873 0.78 SMPD1 (0.49) DPP4GBA1KDM5CHCAR3
SCHEMBL22941083 0.78 GBA1 (0.39) GBA1DRD2KDM5CL3MBTL1CHRNA7
SCHEMBL12452244 0.77 DGAT1 (0.39) FABP7ALDH1A1LMNADRD2CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018067615-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. (US) 2018-04-12 WO disclosed