Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL21359708 | 0.86 | — | — | |
| Potassium Ion SCHEMBL8464792 | 0.86 | — | — | |
| Potassium Ion SCHEMBL56363 | 0.86 | — | — | |
| SCHEMBL21357941 | 0.86 | — | — | |
| Potassium Ion SCHEMBL28913716 | 0.80 | — | — | |
| Potassium Ion SCHEMBL16819020 | 0.80 | — | — | |
| Potassium Ion SCHEMBL28913689 | 0.76 | — | — | |
| Potassium Ion SCHEMBL16671453 | 0.76 | — | — | |
| Tetramethylammonium Ion SCHEMBL2003451 | 0.76 | CHRNB2 (0.44) | — | |
| Potassium Ion SCHEMBL5461201 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319926-A | DURABLE PROTECTIVE COATINGS | PPG INDUSTRIES, INC. (US) | 1982-03-16 | — | — | US | claimed |
| US-20110212271-A1 | HYDROPHILIC COMPOSITIONS, METHODS FOR THEIR PRODUCTION, AND SUBSTRATES COATED WITH SUCH COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7959980-B2 | Hydrophilic compositions, methods for their production, and substrates coated with such compositions | PPG INDUSTRIES OHIO, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-7354650-B2 | Multi-layer coatings with an inorganic oxide network containing layer and methods for their application | PPG INDUSTRIES OHIO, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-7354624-B2 | Applying a photocatalytic liquid and a hydrophilic, ungelled, completely hydrolyzed organosilicate binder directly to the surface of a painted article and curing to form an anti-fouling and/or self-cleaning coating having a dry film thickness of no more than 200 nanometers | PPG INDUSTRIES OHIO, INC. (US) | 2008-04-08 | — | — | US | disclosed |
| EP-1765936-A1 | MULTI-LAYER COATINGS AND RELATED METHODS | PPG Industries Ohio, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1761343-A1 | MULTI-LAYER COATINGS WITH AN INORGANIC OXIDE NETWORK CONTAINING LAYER AND METHODS FOR THEIR APPLICATION | PPG Industries Ohio, Inc. (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1749066-A1 | HYDROPHILIC COMPOSITIONS, METHODS FOR THEIR PRODUCTION, AND SUBSTRATES COATED WITH SUCH COMPOSITIONS | PPG Industries Ohio, Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005118723-A1 | MULTI-LAYER COATINGS AND RELATED METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005118724-A1 | HYDROPHILIC COMPOSITIONS, METHODS FOR THEIR PRODUCTION, AND SUBSTRATES COATED WITH SUCH COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005118163-A1 | MULTI-LAYER COATINGS WITH AN INORGANIC OXIDE NETWORK CONTAINING LAYER AND METHODS FOR THEIR APPLICATION | PPG INDUSTRIES OHIO, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| US-20050266981-A1 | Hydrophilic compositions, methods for their production, and substrates coated with such compositions | PPG INDUSTRIES OHIO, INC. | 2005-12-01 | — | — | US | disclosed |
| US-20050266248-A1 | Multi-layer coatings and related methods | PPG INDUSTRIES OHIO, INC. | 2005-12-01 | — | — | US | disclosed |
| US-20050266235-A1 | Multi-layer coatings with an inorganic oxide network containing layer and methods for their application | PPG INDUSTRIES OHIO, INC. | 2005-12-01 | — | — | US | disclosed |
| US-4383866-A | Metal condensed phosphate hardener coated with reaction product from a metal aluminate and/or a metal borate | PPG INDUSTRIES, INC. (US) | 1983-05-17 | — | — | US | disclosed |
| US-4375496-A | Metal condensed phosphate hardener coated with reaction product from a metal aluminate and/or a metal borate | PPG INDUSTRIES, INC. (US) | 1983-03-01 | — | — | US | disclosed |
| US-4328033-A | Curable silicate composition containing metal condensed phosphate hardener coated with reaction product from a metal aluminate and/or a metal borate | PPG INDUSTRIES, INC. (US) | 1982-05-04 | — | — | US | disclosed |
| US-4319926-A | DURABLE PROTECTIVE COATINGS | PPG INDUSTRIES, INC. (US) | 1982-03-16 | — | — | US | disclosed |
| US-4318743-A | INCLUDING A BASE HAVING A GREATER DEGREE OF BASICITY THAN THE GLASS SILICATE; WATERBASE PAINTS; UNIFORM DISPERSION | PPG INDUSTRIES, INC. (US) | 1982-03-09 | — | — | US | disclosed |