Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20051409 | 0.76 | CYP2C9 (0.46) | CYP2C9CYP2C19SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7153462 | 0.76 | ALOX15 (0.51) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL7322125 | 0.75 | SMN1; SMN2 (0.68) | ALOX12SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL18375516 | 0.75 | ALOX15 (0.55) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL20369609 | 0.75 | ALOX15 (0.55) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL12367132 | 0.74 | ALOX15 (0.50) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL31490121 | 0.74 | ALDH1A1 (0.49) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL9975498 | 0.74 | ALDH1A1 (0.49) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL25084169 | 0.73 | ALOX15 (0.55) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL4014702 | 0.73 | ALOX15 (0.51) | CYP2C9CYP2C19ALOX15ALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | MERCK PATENT GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| EP-3522993-B1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| WO-2018065358-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | SLC14A1, TYR, UROD | CYP2C9 952/4885CYP2C19 456/4885ALOX15 3037/4885 |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | SLC14A1, TYR, UROD | CYP2C9 952/4885CYP2C19 456/4885ALOX15 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.