Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ME3 | Q16798 | 2/20 | 0.42 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552788 | 0.76 | NOTUM (0.50) | NOTUMSMN1; SMN2EPHX2TFPI2MBTD1 | |
| SCHEMBL21397342 | 0.76 | NOTUM (0.50) | NOTUMSMN1; SMN2TFPI2MBTD1L3MBTL3 | |
| SCHEMBL2557623 | 0.76 | NOTUM (0.50) | NOTUMSMN1; SMN2EPHX2TFPI2MBTD1 | |
| SCHEMBL2554913 | 0.76 | GPR119 (0.54) | GPR119KMT2AMMP2 | |
| SCHEMBL22552563 | 0.75 | ITGB3 (0.48) | SMN1; SMN2ME3ALDH1A1POLB | |
| SCHEMBL22552564 | 0.75 | ITGB3 (0.48) | SMN1; SMN2ME3ALDH1A1POLB | |
| SCHEMBL7160514 | 0.73 | MBTD1 (0.52) | NOTUMTFPI2MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL10360107 | 0.73 | NOTUM (0.50) | NOTUMSMN1; SMN2EPHX2TFPI2MBTD1 | |
| SCHEMBL8698089 | 0.72 | ITGB3 (0.43) | TSHR | |
| SCHEMBL18155148 | 0.72 | L3MBTL1 (0.50) | NOTUMSMN1; SMN2MBTD1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066545-A1 | HETEROCYCLIC COMPOUND | 公益財団法人ヒューマンサイエンス振興財団 | 2018-04-12 | — | — | WO | disclosed |