SCHEMBL20051989

SCHEMBL20051989

CC(=O)O[C@@H](CCN=[N+]=[N-])C(O)NC(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17586046 0.72 TRPV1 (0.33) TRPV1
SCHEMBL16271230 0.72 TRPV1 (0.33) TRPV1
SCHEMBL16456852 0.69 TDP1 (0.37) —
SCHEMBL18721927 0.68 MMP2 (0.30) —
SCHEMBL15251520 0.68 MMP2 (0.30) —
SCHEMBL23690559 0.67 TSHR (0.30) —
SCHEMBL23747679 0.67 CTSL (0.31) —
SCHEMBL15892790 0.66 TDP1 (0.47) TRPV1
SCHEMBL19501730 0.66 — —
SCHEMBL14110657 0.63 TSHR (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943533-B2 Aminoglycosides and uses thereof in treating genetic disorders TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2018-04-17 — — US disclosed
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