Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586046 | 1.00 | TRPV1 (0.33) | TRPV1MMP2ANPEPTSHR | |
| SCHEMBL15251520 | 0.84 | MMP2 (0.30) | MMP2ANPEP | |
| SCHEMBL18721927 | 0.84 | MMP2 (0.30) | MMP2ANPEP | |
| SCHEMBL19501730 | 0.82 | — | — | |
| SCHEMBL23690559 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL16271225 | 0.77 | TRPV1 (0.39) | TRPV1TSHR | |
| SCHEMBL22605301 | 0.73 | TSHR (0.39) | TRPV1MMP2TSHR | |
| SCHEMBL17906289 | 0.73 | CTSL (0.32) | — | |
| SCHEMBL20051989 | 0.72 | TRPV1 (0.36) | TRPV1 | |
| SCHEMBL13396864 | 0.68 | TSHR (0.46) | TRPV1MMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228608-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2021-07-29 | — | — | US | disclosed |
| US-10973839-B2 | Aminoglycosides and uses thereof in treating genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2021-04-13 | — | — | US | disclosed |
| US-10398718-B2 | Aminoglycosides and uses thereof in treating genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-09-03 | — | — | US | disclosed |
| US-20190224226-A9 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2019-07-25 | — | — | US | disclosed |
| US-20180200276-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-07-19 | — | — | US | disclosed |
| US-20180200276-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-07-19 | — | — | US | disclosed |
| US-9943533-B2 | Aminoglycosides and uses thereof in treating genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-04-17 | — | — | US | disclosed |
| US-9943533-B2 | Aminoglycosides and uses thereof in treating genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2018-04-17 | — | — | US | disclosed |
| US-20170182078-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-06-29 | — | — | US | disclosed |
| US-9616079-B2 | Aminoglycosides and uses thereof in treating genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2017-04-11 | — | — | US | disclosed |
| US-20160074425-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2016-03-17 | — | — | US | disclosed |
| US-9175029-B2 | Aminoglycosides and uses thereof in treating genetic disorders | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2015-11-03 | — | — | US | disclosed |
| US-20140357590-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182078-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-20180200276-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-20140357590-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-10398718-B2 | Aminoglycosides and uses thereof in treating genetic disorders | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-20210228608-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-10973839-B2 | Aminoglycosides and uses thereof in treating genetic disorders | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-20160074425-A1 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
| US-20190224226-A9 | AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS | AARS1, GARS1, UPF1 | TRPV1 4150/4885MMP2 4191/4885ANPEP 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.