Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.62 |
| ▸ | CASP7 | P55210 | 8/20 | 0.62 |
| ▸ | CASP1 | P29466 | 8/20 | 0.61 |
| ▸ | CASP9 | P55211 | 3/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | CASP4 | P49662 | 2/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462658 | 1.00 | CASP3 (0.62) | CASP3CASP7CASP1CASP9OPRD1 | |
| SCHEMBL29946109 | 0.87 | CASP1 (0.61) | CASP3CASP7CASP1OPRD1 | |
| SCHEMBL29408005 | 0.83 | OPRD1 (0.68) | CASP1OPRD1 | |
| SCHEMBL4735755 | 0.80 | OPRD1 (0.65) | CASP1OPRD1 | |
| SCHEMBL31404908 | 0.79 | OPRD1 (0.66) | CASP1OPRD1 | |
| SCHEMBL4735748 | 0.79 | OPRD1 (0.61) | CASP1OPRD1 | |
| SCHEMBL15462665 | 0.78 | CASP3 (0.93) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL478003 | 0.78 | OPRD1 (0.62) | CASP1OPRD1 | |
| SCHEMBL31265324 | 0.78 | OPRD1 (0.56) | OPRD1 | |
| SCHEMBL22644029 | 0.78 | OPRD1 (0.55) | CASP1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2021-04-13 | — | — | US | disclosed |
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-07-05 | — | — | US | disclosed |
| US-9944674-B2 | Selective cysteine protease inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2018-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186833-A1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | SERPINB1, SERPINE1, CASP5 | CASP3 146/4885CASP7 102/4885CASP1 25/4885 |
| US-10975119-B2 | Selective cysteine protease inhibitors and uses thereof | SERPINB1, SERPINE1, CASP5 | CASP3 171/4885CASP7 129/4885CASP1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.