Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.40 |
| ▸ | FEN1 | P39748 | 5/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539418 | 0.90 | GPR119 (0.42) | GPR119ALOX5APFEN1PARP10PARP15 | |
| SCHEMBL20053647 | 0.89 | MCHR1 (0.39) | GPR119ALOX5APFEN1PARP10PARP15 | |
| SCHEMBL15539640 | 0.88 | GPR119 (0.41) | GPR119ALOX5APFEN1P2RY1CYP4F2 | |
| SCHEMBL20053598 | 0.87 | GPR119 (0.46) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15538821 | 0.87 | CNR2 (0.42) | GPR119ALOX5APFEN1PARP10PARP15 | |
| SCHEMBL15538816 | 0.87 | CNR2 (0.42) | GPR119ALOX5APFEN1PARP10PARP15 | |
| SCHEMBL20053594 | 0.85 | GPR119 (0.46) | GPR119ADRB2CYP4F2CYP4A11 | |
| SCHEMBL20053739 | 0.83 | ADRB2 (0.45) | GPR119ADRB2KCNH2 | |
| SCHEMBL20053536 | 0.83 | GPR119 (0.40) | GPR119ALOX5APFEN1ADRB2KCNH2 | |
| SCHEMBL15539450 | 0.82 | ALOX5AP (0.41) | GPR119ALOX5APFEN1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |