Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053741 | 0.91 | GPR119 (0.44) | GPR119HRH3BCHEACHEHPGD | |
| SCHEMBL15539249 | 0.89 | ACHE (0.43) | GPR119BCHEACHESMN1; SMN2HPGDS | |
| SCHEMBL21534807 | 0.88 | GPR119 (0.43) | GPR119HRH3HPGDKDM4EL3MBTL1 | |
| SCHEMBL15539245 | 0.88 | HPGDS (0.41) | GPR119BCHEACHEKDM4EHPGDS | |
| SCHEMBL21534617 | 0.88 | BCHE (0.36) | GPR119HRH3BCHEACHEL3MBTL1 | |
| SCHEMBL20053648 | 0.87 | CYP2D6 (0.44) | GPR119HRH3ACHEHPGDALDH1A1 | |
| SCHEMBL15538711 | 0.86 | SPHK1 (0.42) | BCHEACHEL3MBTL1ALDH1A1 | |
| SCHEMBL15538815 | 0.86 | SPHK1 (0.42) | BCHEACHEL3MBTL1ALDH1A1 | |
| SCHEMBL20053540 | 0.86 | GPR119 (0.56) | GPR119HRH3HPGDKDM4EL3MBTL1 | |
| SCHEMBL15538353 | 0.83 | GRM3 (0.40) | GPR119HRH3BCHEACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |