Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19113313 | 0.88 | CARM1 (0.56) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL19113186 | 0.86 | CHRM2 (0.55) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL4277358 | 0.85 | CHRM2 (0.52) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL4272776 | 0.84 | EPHX2 (0.52) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL19112915 | 0.84 | EPHX2 (0.52) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL13569865 | 0.83 | HDAC6 (0.50) | CACNA1IKCNH2CHRM4HDAC6HDAC3 | |
| SCHEMBL4284039 | 0.83 | CHRM2 (0.51) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL19112914 | 0.82 | EPHX2 (0.50) | CHRM2CHRM1EPHX2CXCR3CACNA1I | |
| SCHEMBL11758042 | 0.82 | CXCR3 (0.64) | CHRM2CHRM1EPHX2CXCR3PREP | |
| SCHEMBL19112876 | 0.80 | CACNA1I (0.50) | CHRM2CHRM1EPHX2CACNA1IKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | PRAXIS PREC MEDICINES INC (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-2300007-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | TARO PHARMACEUTICALS INC (CA) | 2018-04-18 | — | — | EP | disclosed |