SCHEMBL4272776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4277358	0.89	CHRM2 (0.52)	EPHX2CHRM2CHRM1CXCR3CHRM4
	SCHEMBL4270009	0.89	KCNH2 (0.48)	CHRM2CHRM1CHRM4CACNA1IKCNH2
	SCHEMBL4284039	0.88	CHRM2 (0.51)	EPHX2CHRM2CHRM1CXCR3CHRM4
	SCHEMBL19113313	0.85	CARM1 (0.56)	EPHX2CHRM2CHRM1CXCR3CHRM4
	SCHEMBL4280597	0.84	ALDH1A1 (0.52)	EPHX2CACNA1IKCNH2HDAC6HDAC3
	SCHEMBL20056282	0.84	CHRM2 (0.55)	EPHX2CHRM2CHRM1CXCR3CHRM4
	SCHEMBL19112915	0.83	EPHX2 (0.52)	EPHX2CHRM2CHRM1CXCR3CHRM4
	SCHEMBL19113186	0.83	CHRM2 (0.55)	EPHX2CHRM2CHRM1CXCR3CHRM4
	SCHEMBL4272143	0.82	KCNH2 (0.47)	GSK3BCACNA1IKCNH2HDAC6KDM1A
	SCHEMBL4272500	0.81	KCNH2 (0.66)	CACNA1IKCNH2CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.