SCHEMBL4277358

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4272776	0.89	EPHX2 (0.52)	CHRM2CHRM1CXCR3EPHX2GSK3B
	SCHEMBL4274696	0.89	KCNH2 (0.48)	CHRM2CHRM1GSK3BCHRM4CACNA1I
	SCHEMBL4284039	0.89	CHRM2 (0.51)	CHRM2CHRM1CXCR3EPHX2GSK3B
	SCHEMBL19113313	0.86	CARM1 (0.56)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL20056282	0.85	CHRM2 (0.55)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL19113186	0.83	CHRM2 (0.55)	CHRM2CHRM1CXCR3EPHX2CHRM4
	SCHEMBL4279234	0.82	MAPT (0.51)	GSK3BCACNA1IKCNH2CACNA1HCYP2D6
	SCHEMBL4277778	0.82	HTR4 (0.56)	GSK3BCACNA1IKCNH2CACNA1HCYP2D6
	SCHEMBL4272977	0.82	CACNA1I (0.52)	CACNA1IKCNH2HDAC6KDM1ACACNA1H
	SCHEMBL4282823	0.82	KCNH2 (0.52)	GSK3BCHRM4CACNA1IKCNH2CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.