Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29754142 | 0.83 | RAB9A (0.52) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL637319 | 0.83 | RAB9A (0.52) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL2469671 | 0.81 | RAB9A (0.53) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL29519716 | 0.81 | RAB9A (0.53) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL2008134 | 0.81 | ACHE (0.49) | NPC1RAB9AACHETAAR1IDO1 | |
| Bromide SCHEMBL504672 | 0.80 | SMN1; SMN2 (0.57) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| Bromide SCHEMBL30982171 | 0.80 | SMN1; SMN2 (0.57) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| SCHEMBL16079011 | 0.75 | RAB9A (0.43) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28524885 | 0.74 | NPC1 (0.46) | NPC1POLBRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL23499618 | 0.72 | CA1 (0.44) | POLBLMNAKDM4ETAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8182557-B2 | Pretreating lignocellulosic (woody biomass) by dissolving in ionic liquid comprising imidazolium or pyridinium salt to form a solution; precipitating with regenerating solvent (water); hydrolysis to form sugar and fermentation to form bioethanol; recycling through evaporation; environmentally friendly | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-22 | — | — | US | disclosed |
| US-7959765-B2 | Dissolving in liquid; pyrolysis | NORTH CAROLINA STATE UNIVERSTIY (US) | 2011-06-14 | — | — | US | disclosed |
| US-20080190013-A1 | USE OF LIGNOCELLULOSICS SOLVATED IN IONIC LIQUIDS FOR PRODUCTION OF BIOFUELS | NORTH CAROLINA STATE UNIVERSITY | 2008-08-14 | — | — | US | disclosed |
| US-20080188636-A1 | POLYMER DERIVATIVES AND COMPOSITES FROM THE DISSOLUTION OF LIGNOCELLULOSICS IN IONIC LIQUIDS | NORTH CAROLINA STATE UNIVERSITY | 2008-08-07 | — | — | US | disclosed |
| US-20080185112-A1 | PRODUCT PREPARATION AND RECOVERY FROM THERMOLYSIS OF LIGNOCELLULOSICS IN IONIC LIQUIDS | NORTH CAROLINA STATE UNIVERSITY | 2008-08-07 | — | — | US | disclosed |