Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | SLC19A2 | O60779 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL637319 | 1.00 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL29519716 | 0.98 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| SCHEMBL2469671 | 0.98 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Bromide SCHEMBL504672 | 0.96 | SMN1; SMN2 (0.57) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Bromide SCHEMBL30982171 | 0.96 | SMN1; SMN2 (0.57) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL28524885 | 0.85 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL2005677 | 0.83 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL8857341 | 0.80 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Bromide SCHEMBL5763149 | 0.79 | KMT2A (0.49) | RAB9ANPC1SMN1; SMN2POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL2008134 | 0.78 | ACHE (0.49) | RAB9ANPC1CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115895622-B | Composition with hydrate inhibition function, preparation method and application | 中国石油化工股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-112012000-B | Fiber surface treatment method, fiber-reinforced anticorrosive paint and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-09-02 | — | — | CN | claimed |
| CN-113717562-B | Efficient antibacterial latex composition and preparation method thereof | 北京崇高纳米科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-115885995-B | Composition with sterilization performance and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20240377745-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION AND SILICON-CONTAINING RESIST UNDERLAYER FILM | NISSAN CHEMICAL CORPORATION (JP) | 2024-11-14 | — | — | US | disclosed |
| US-20240231230-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM | NISSAN CHEMICAL CORPORATION (JP) | 2024-07-11 | — | — | US | disclosed |
| CN-118187795-A | Flexible storage method for dry-hot rock | 成都理工大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-115895622-B | Composition with hydrate inhibition function, preparation method and application | 中国石油化工股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-112012000-B | Fiber surface treatment method, fiber-reinforced anticorrosive paint and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-09-02 | — | — | CN | disclosed |
| CN-113717562-B | Efficient antibacterial latex composition and preparation method thereof | 北京崇高纳米科技有限公司 | 2022-07-29 | — | — | CN | disclosed |