SCHEMBL2942491

SCHEMBL2942491

CN(C)c1ccccc1NC(N)=O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 1/20 0.50
GAA P10253 4/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 3/20 0.48
TSHR P16473 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MAPT P10636 2/20 0.48
TP53 P04637 1/20 0.48
RECQL P46063 1/20 0.45
POLB P06746 1/20 0.44
NAMPT P43490 1/20 0.42
LMNA P02545 1/20 0.42
GFER P55789 1/20 0.41
KDM1A O60341 1/20 0.41
CYP1A2 P05177 1/20 0.41
HDAC3 O15379 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MASP2 O00187 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3648636 0.84 ALDH1A1 (0.57) KCNQ2GAAKDM4EALDH1A1TSHR
SCHEMBL8779736 0.84 KCNQ2 (0.50) KCNQ2GAAKDM4EALDH1A1TSHR
SCHEMBL7814232 0.82 L3MBTL1 (0.53) KCNQ2GAAKDM4EALDH1A1TSHR
SCHEMBL30356302 0.82 L3MBTL1 (0.53) KCNQ2GAAKDM4EALDH1A1TSHR
SCHEMBL11775098 0.82 KCNQ2 (0.52) KCNQ2GAAKDM4EALDH1A1TSHR
SCHEMBL20057526 0.82 ALDH1A1 (0.49) KCNQ2GAAALDH1A1TSHRSMN1; SMN2
SCHEMBL20324021 0.81 ALDH1A1 (0.68) KCNQ2GAAKDM4EALDH1A1TSHR
SCHEMBL11741095 0.81 GPR35 (0.52) KCNQ2GAAALDH1A1TSHRSMN1; SMN2
SCHEMBL29840068 0.80 GAA (0.67) GAAKDM4EALDH1A1SMN1; SMN2MAPT
SCHEMBL3928666 0.80 GAA (0.67) GAAKDM4EALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300172-B Bruton tyrosine kinase inhibitors 比奥根MA公司 2024-01-16 CN disclosed
EP-4203911-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME L'OREAL (FR) 2023-07-05 EP disclosed
EP-4203904-A1 COSMETIC COMPOSITIONS, KITS THEREOF, AND METHODS FOR MAKING AND USING THE SAME L'OREAL (FR) 2023-07-05 EP disclosed
CN-108495613-B Composition for treating hair 欧莱雅 2021-12-10 CN disclosed
CN-102665924-B Personal care composition foamed products and foaming dispenser THE PROCTER & GAMBLE CO. (US) 2015-12-02 CN disclosed
CN-102655942-B Personal care composition foamed products THE PROCTER & GAMBLE CO. (US) 2015-08-12 CN disclosed
CN-102917683-B Porous dissolvable solid substrate and surface resident coating comprising water sensitive active THE PROCTER & GAMBLE CO. (US) 2015-08-05 CN disclosed
CN-103841951-A Foam oxidative hair colorant composition with the free-base of 1, 4-diamino-2-methoxmethyl benzene PROCTER & GAMBLE 2014-06-04 CN disclosed
CN-102917683-A Porous dissolvable solid substrate and surface resident coating comprising water sensitive active PROCTER & GAMBLE 2013-02-06 CN disclosed
CN-102665924-A Personal care composition foaming product and foaming dispenser PROCTER & GAMBLE 2012-09-12 CN disclosed
EP-1345580-B1 COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND OREAL (FR) 2006-06-07 EP disclosed
EP-1333792-A4 NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING P & G CLAIROL INC (US) 2005-08-10 EP disclosed
EP-1487841-A1 THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS Abbott Laboratories (US) 2004-12-22 EP disclosed
WO-2003080625-A1 THIOPYRIMIDINE AND ISOTHIAZOLOPYRIMIDINE KINASE INHIBITORS ABBOTT LABORATORIES (US) 2003-10-02 WO disclosed
EP-1333792-A1 NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING P & G-Clairol, Inc. (US) 2003-08-13 EP disclosed
US-6577591-B2 Optical recording medium KABUSHIKI KAISHA TOSHIBA (JP) 2003-06-10 US disclosed
WO-2002039967-A1 NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING P&G - CLAIROL, INC. (US) 2002-05-23 WO disclosed
US-20010030935-A1 Optical recording medium KABUSHIKI KAISHA TOSHIBA (JP) 2001-10-18 US disclosed
EP-0628033-A1 BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1994-12-14 EP disclosed
US-5283362-A Reacting with an amine, terminating the reaction before the formation of by-product CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1994-02-01 US disclosed