Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846258 | 0.93 | L3MBTL1 (0.40) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL846068 | 0.89 | KDM4E (0.42) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL846336 | 0.89 | ADORA2A (0.43) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL879472 | 0.88 | ADORA2A (0.40) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL846130 | 0.85 | L3MBTL1 (0.44) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL1254725 | 0.83 | L3MBTL1 (0.45) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL846745 | 0.82 | ROCK2 (0.47) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL1255710 | 0.81 | L3MBTL1 (0.46) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL19112468 | 0.81 | ADORA2A (0.37) | KDM4EHPGDALDH1A1POLBNPC1 | |
| SCHEMBL19407357 | 0.81 | PLTP (0.41) | KDM4EHPGDALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433938-B1 | THERAPEUTIC AGENT FOR MOTOR DISORDERS | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-04-18 | — | — | EP | disclosed |