SCHEMBL846068

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL879472	0.94	ADORA2A (0.40)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL846336	0.92	ADORA2A (0.43)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL846258	0.90	L3MBTL1 (0.40)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL20057575	0.89	KDM4E (0.40)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL846130	0.88	L3MBTL1 (0.44)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL13066202	0.86	ADORA2A (0.36)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL1254725	0.85	L3MBTL1 (0.45)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL846745	0.85	ROCK2 (0.47)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL19407315	0.85	ADORA2A (0.35)	KDM4EADORA2AADORA1ALDH1A1POLB
	SCHEMBL1255710	0.83	L3MBTL1 (0.46)	KDM4EADORA2AADORA1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.