SCHEMBL846745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL879501	0.94	KDM5C (0.44)	ROCK2WNT1GSK3BDYRK1AADORA2A
	SCHEMBL846130	0.89	L3MBTL1 (0.44)	ADORA2AADORA1MEN1MAPTKMT2A
	SCHEMBL1254213	0.87	ADORA2A (0.52)	ROCK2ADORA2AADORA1
	SCHEMBL1256698	0.87	SMN1; SMN2 (0.48)	ROCK2ADORA2AADORA1KMT2AL3MBTL1
	SCHEMBL846336	0.86	ADORA2A (0.43)	ADORA2AADORA1MEN1MAPTKMT2A
	SCHEMBL846068	0.85	KDM4E (0.42)	ADORA2AADORA1MEN1MAPTKMT2A
	SCHEMBL19407339	0.84	ADORA2A (0.39)	ROCK2ADORA2AADORA1MEN1MAPT
	SCHEMBL846258	0.84	L3MBTL1 (0.40)	ADORA2AADORA1MEN1MAPTKMT2A
	SCHEMBL1254725	0.84	L3MBTL1 (0.45)	ADORA2AADORA1MEN1MAPTKMT2A
	SCHEMBL1255710	0.84	L3MBTL1 (0.46)	ADORA2AADORA1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.