SCHEMBL2005779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2011874	0.91	PTGDR2 (0.57)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL2007754	0.89	AKR1C3 (0.51)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL2009192	0.89	PTGDR2 (0.61)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL2008346	0.87	PPARG (0.51)	PTGDR2PLA2G2APLA2G1BALOX5LMNA
	SCHEMBL2996259	0.86	PTGDR2 (0.60)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL4543998	0.82	PLA2G2A (0.50)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL3006501	0.82	PTGDR2 (0.64)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL2006287	0.82	PLA2G2A (0.66)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL2005221	0.82	PTGDR2 (0.66)	PTGDR2PLA2G2APLA2G1BPTGESALOX5
	SCHEMBL15062720	0.82	PLA2G2A (0.43)	PLA2G2APLA2G1BALOX5CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.