Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681661 | 0.82 | CYP19A1 (0.63) | LMNAPSMD14POLBCA1CA2 | |
| SCHEMBL955942 | 0.82 | CYP19A1 (0.63) | LMNAPSMD14POLBCA1CA2 | |
| SCHEMBL29405472 | 0.82 | CYP19A1 (0.63) | LMNAPSMD14POLBCA1CA2 | |
| SCHEMBL1223439 | 0.80 | P2RX4 (0.68) | LMNAPSMD14POLBMAPTALDH1A1 | |
| SCHEMBL22700981 | 0.77 | LMNA (0.53) | LMNAPSMD14POLBTP53MAPT | |
| SCHEMBL20806246 | 0.75 | CA12 (0.54) | LMNAPSMD14POLBCA1CA2 | |
| SCHEMBL19941907 | 0.75 | P2RX4 (0.42) | CA1CA2CYP19A1L3MBTL1P2RX4 | |
| SCHEMBL28337505 | 0.75 | LMNA (0.51) | LMNAPSMD14TP53MAPTALDH1A1 | |
| SCHEMBL17457937 | 0.73 | PSMD14 (0.53) | LMNAPSMD14POLBTP53MAPT | |
| SCHEMBL16627135 | 0.71 | PSMD14 (0.51) | LMNAPSMD14TP53MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078691-B1 | BLOCK COPOLYMER | LG CHEMICAL LTD (KR) | 2018-04-18 | — | — | EP | disclosed |