Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | NPM1 | P06748 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31165289 | 1.00 | PSMD14 (0.51) | PSMD14LMNATP53MAPTCYP19A1 | |
| SCHEMBL28337505 | 0.92 | LMNA (0.51) | PSMD14LMNATP53MAPTCYP19A1 | |
| SCHEMBL30681661 | 0.87 | CYP19A1 (0.63) | PSMD14LMNACYP19A1MEN1KMT2A | |
| SCHEMBL955942 | 0.87 | CYP19A1 (0.63) | PSMD14LMNACYP19A1MEN1KMT2A | |
| SCHEMBL29405472 | 0.87 | CYP19A1 (0.63) | PSMD14LMNACYP19A1MEN1KMT2A | |
| SCHEMBL17457937 | 0.86 | PSMD14 (0.53) | PSMD14LMNATP53MAPTCYP19A1 | |
| SCHEMBL2246814 | 0.84 | CYP19A1 (0.70) | TP53MAPTCYP19A1DNM1MEN1 | |
| SCHEMBL25841829 | 0.83 | CYP19A1 (0.64) | PSMD14LMNAMAPTCYP19A1MEN1 | |
| SCHEMBL10064304 | 0.83 | PSMD14 (0.50) | PSMD14LMNATP53MAPTCYP19A1 | |
| SCHEMBL8173916 | 0.82 | CYP19A1 (0.57) | TP53MAPTCYP19A1DNM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053910-B1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| EP-3053910-B1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-10700283-B2 | Aniline derivatives and uses thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| CN-105793233-B | Anil and its utilization | 日产化学工业株式会社 | 2019-03-08 | — | — | CN | disclosed |
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-13 | — | — | US | disclosed |
| EP-3053910-A1 | ANILINE DERIVATIVES AND USES THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| EP-3053910-A1 | ANILINE DERIVATIVES AND USES THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050253-A1 | ANILINE DERIVATIVES AND USES THEREOF | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | SLC18A1, SLC18A2, SLC43A1 | PSMD14 4153/4885LMNA 1442/4885TP53 4807/4885 |
| US-10700283-B2 | Aniline derivatives and uses thereof | SLC18A1, SLC18A2, SLC43A1 | PSMD14 4153/4885LMNA 1442/4885TP53 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.