Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061130 | 1.00 | SIGMAR1 (0.56) | SIGMAR1TAAR1SLC18A2SLC6A4ADRB2 | |
| SCHEMBL11749423 | 0.77 | SIGMAR1 (0.42) | SIGMAR1TAAR1SLC18A2HTR1AADRA1A | |
| SCHEMBL27740328 | 0.76 | SLC6A4 (0.54) | SIGMAR1TAAR1SLC18A2SLC6A4SLC6A2 | |
| SCHEMBL27010643 | 0.76 | KDM1A (0.47) | CYP3A4 | |
| SCHEMBL20063373 | 0.76 | KDM1A (0.47) | CYP3A4 | |
| SCHEMBL33991 | 0.74 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL3681409 | 0.74 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL28281562 | 0.74 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC18A2MEN1KMT2A | |
| SCHEMBL4883252 | 0.73 | SLC6A4 (0.51) | SIGMAR1TAAR1SLC18A2SLC6A4CYP2D6 | |
| SCHEMBL28219352 | 0.73 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC18A2SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105477-A1 | A METHOD FOR PREPARING OPTICALLY ACTIVE CARBONYL COMPOUND | ZHEJIANG NHU COMPANY LTD. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180105477-A1 | A METHOD FOR PREPARING OPTICALLY ACTIVE CARBONYL COMPOUND | ZHEJIANG NHU COMPANY LTD. (CN) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105477-A1 | A METHOD FOR PREPARING OPTICALLY ACTIVE CARBONYL COMPOUND | TPSD1, QDPR, TALDO1 | SIGMAR1 642/4885TAAR1 1110/4885SLC18A2 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.