SCHEMBL33991

SCHEMBL33991

CC(Cc1ccccc1)NC1OCO1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 10/20 0.52
TAAR1 Q96RJ0 3/20 0.52
SLC18A2 Q05940 1/20 0.52
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5653344 0.98 SIGMAR1 (0.50) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL3681409 0.90 SIGMAR1 (0.52) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL497585 0.78 SIGMAR1 (0.46) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL20061130 0.74 SIGMAR1 (0.56) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL20061148 0.74 SIGMAR1 (0.56) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL13154126 0.73 GAA (0.55) SIGMAR1MEN1KMT2ACYP1A2CYP3A4
SCHEMBL17479478 0.71 SIGMAR1 (0.50) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL30624762 0.71 SIGMAR1 (0.71) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL21243273 0.71 SIGMAR1 (0.73) SIGMAR1TAAR1SLC18A2MEN1KMT2A
SCHEMBL13537546 0.71 SIGMAR1 (0.47) SIGMAR1TAAR1SLC18A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1994 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122016983-A Method for detecting multiple drugs in hair 公安部鉴定中心 2026-05-12 CN claimed
CN-122028945-A Apparatus, systems, and methods for aerosolized drug administration GH研究爱尔兰有限公司 2026-05-12 CN claimed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-20260060949-A1 METHOD FOR TREATING DAMAGE INDUCED BY SLEEP DEPRIVATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-05 US claimed
US-20250352538-A1 PHARMACEUTICAL RESINATE COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF RHODES PHARMACEUTICALS LP (US) 2025-11-20 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
EP-4594294-A1 DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2025-08-06 EP claimed
US-12377065-B2 Compositions for treatment of substance use disorder UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER (US) 2025-08-05 US claimed
US-20250195537-A1 PSYCHEDELIC DRUG TREATMENT OF NEUROPSYCHIATRIC DISORDERS AND CEREBRAL PALSY FEIFEL DAVID (US) 2025-06-19 US claimed
CN-117654455-B Purifying and extracting composition, kit and method for determining drugs and fentanyl drugs in biological sample 宁波市疾病预防控制中心(宁波市健康教育与促进中心) 2025-06-10 CN claimed
EP-1242058-A1 USE OF CYP2D6 INHIBITORS IN COMBINATION THERAPIES Pfizer Products Inc. (US) 2002-09-25 EP claimed
US-20020042446-A1 Treatment of addiction and addiction-related behavior BROOKHAVEN SCIENCE ASSOCIATES 2002-04-11 US claimed
US-20020037925-A1 Treatment of addiction and addiction-related behavior BROOKHAVEN SCIENCE ASSOCIATES 2002-03-28 US claimed
US-20020019421-A1 Compositions and therapy for substance addiction BIBERMAN RONI (IL) 2002-02-14 US claimed
EP-1121591-A1 IMMUNOASSAY THAT PROVIDES FOR BOTH COLLECTION OF SALIVA AND ASSAY OF SALIVA Bogema, Stuart C. (US) 2001-08-08 EP claimed
WO-2000015020-A9 IMMUNOASSAY THAT PROVIDES FOR BOTH COLLECTION OF SALIVA AND ASSAY OF SALIVA BOGEMA STUART C (US) 2001-06-21 WO claimed
US-6248598-B1 Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout BOGEMA STUART C (US) 2001-06-19 US claimed
WO-2000059486-A2 USE OF CYP2D6 INHIBITORS IN COMBINATION THERAPIES PFIZER PRODUCTS INC. (US) 2000-10-12 WO claimed
WO-2000015020-A1 IMMUNOASSAY THAT PROVIDES FOR BOTH COLLECTION OF SALIVA AND ASSAY OF SALIVA BOGEMA STUART C (US) 2000-03-23 WO claimed
WO-2000006139-A2 USE OF MOCLOBEMIDE AND METABOLITES FOR TREATING AND PREVENTING SUBSTANCE ABUSE VELA PHARMACEUTICALS INC. (US) 2000-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060949-A1 METHOD FOR TREATING DAMAGE INDUCED BY SLEEP DEPRIVATION ATP2A1, CHERP, ATP2A3 SIGMAR1 927/4885TAAR1 4207/4885SLC18A2 794/4885
US-12377065-B2 Compositions for treatment of substance use disorder PNMT, METTL3, BHMT2 SIGMAR1 138/4885TAAR1 124/4885SLC18A2 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.