Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | TSHR | P16473 | 1/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.98 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.98 |
| ▸ | LMNA | P02545 | 3/20 | 0.96 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Telenzepine SCHEMBL49345 | 0.99 | CYP2D6 (1.00) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| Telenzepine SCHEMBL184401 | 0.98 | LMNA (1.00) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| Telenzepine SCHEMBL970991 | 0.98 | LMNA (1.00) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| Telenzepine SCHEMBL14973496 | 0.97 | ALDH1A1 (0.96) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11192698 | 0.91 | ALDH1A1 (0.85) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9431778 | 0.89 | ALDH1A1 (0.82) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9727995 | 0.89 | ALDH1A1 (0.81) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11187135 | 0.88 | CYP2D6 (0.80) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| Pirenzepine SCHEMBL935909 | 0.88 | ALDH1A1 (0.79) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9431091 | 0.87 | ALDH1A1 (0.78) | CYP2D6ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964361-B2 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090281279-A1 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-12 | — | — | US | disclosed |
| US-7408062-B2 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY (US) | 2008-08-05 | — | — | US | disclosed |
| US-20070243527-A9 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE MELLON UNIVERSITY | 2007-10-18 | — | — | US | disclosed |
| US-6686145-B1 | IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS BY COVALENT AND NONCOVALENT ASSOCIATION | CARNEGIE MELLON UNIVERSITY | 2004-02-03 | — | — | US | disclosed |
| US-20030224391-A1 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY | 2003-12-04 | — | — | US | disclosed |
| EP-1042407-B1 | RIGIDIZED TRIMETHINE CYANINE DYES | UNIV CARNEGIE MELLON (US) | 2001-09-12 | — | — | EP | disclosed |
| US-6133445-A | USEFUL FOR IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS | CARNEGIE MELLON UNIVERSITY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1042407-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE-MELLON UNIVERSITY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031181-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE MELLON UNIVERSITY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070243527-A9 | RIGIDIZED TRIMETHINE CYANINE DYES | SIGMAR1, CBR1, NR0B1 | CYP2D6 566/4885ALDH1A1 1428/4885CYP1A2 272/4885 |
| US-20090281279-A1 | Rigidized trimethine cyanine dyes | CD47, TLN1, TPM4 | CYP2D6 4003/4885ALDH1A1 3193/4885CYP1A2 3515/4885 |
| US-20030224391-A1 | Rigidized trimethine cyanine dyes | CBR1, TH, CBR3 | CYP2D6 1565/4885ALDH1A1 2154/4885CYP1A2 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.