Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20147340 | 0.89 | EPHX1 (0.34) | EPHX1SMYD3 | |
| SCHEMBL20069718 | 0.76 | EPHX1 (0.39) | EPHX1SMYD3 | |
| SCHEMBL20147339 | 0.69 | WNT1 (0.37) | SMYD3 | |
| SCHEMBL18314607 | 0.66 | CTSL (0.39) | EPHX1 | |
| SCHEMBL20147475 | 0.66 | CCR1 (0.34) | — | |
| SCHEMBL17033020 | 0.66 | EPHX1 (0.41) | EPHX1 | |
| SCHEMBL20147467 | 0.65 | TP53 (0.38) | — | |
| SCHEMBL19009045 | 0.65 | CHRNB2 (0.44) | EPHX1 | |
| SCHEMBL20147307 | 0.64 | SIGMAR1 (0.32) | — | |
| SCHEMBL20147471 | 0.63 | SIGMAR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |