SCHEMBL2006973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2002221	0.87	PGR (0.40)	PGRNR3C1CYP11B2XDHMAPK14
	SCHEMBL27778418	0.81	SLC2A1 (0.42)	PGRNR3C1XDHMAPK14MEN1
	SCHEMBL2005406	0.79	FFAR4 (0.38)	MEN1KMT2A
	SCHEMBL4439652	0.78	PGR (0.34)	PGRNR3C1CYP11B2CYP11B1
	SCHEMBL12572499	0.76	CYP11B1 (0.30)	CYP11B2CYP11B1
	SCHEMBL2006324	0.75	MAPT (0.37)	XDHMAPK14
	SCHEMBL2006080	0.74	CYP11B2 (0.46)	PGRNR3C1CYP11B2CYP11B1MEN1
	SCHEMBL198609	0.68	TTR (0.52)	TTRALBMEN1KMT2A
	SCHEMBL2006894	0.68	NR3C1 (0.38)	PGRNR3C1CYP11B2CYP11B1
	SCHEMBL1135640	0.67	MAPK14 (0.49)	PGRNR3C1XDHMAPK14MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.