SCHEMBL200710

SCHEMBL200710

NCc1ccccc1-c1ccccc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.54
DPP4 P27487 2/20 0.53
MYC P01106 1/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX12 P18054 1/20 0.49
ALDH1A1 P00352 3/20 0.48
ALOX15 P16050 1/20 0.48
HMGB1 P09429 2/20 0.47
HTT P42858 1/20 0.46
GAA P10253 1/20 0.46
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 1/20 0.43
HNF4A P41235 1/20 0.43
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2242560 0.85 BCAT2 (0.55) FOLH1DPP4ALDH1A1GAATSHR
SCHEMBL136079 0.84 FOLH1 (0.59) FOLH1DPP4ALDH1A1ALOX15HMGB1
SCHEMBL28324262 0.84 FOLH1 (0.59) FOLH1DPP4ALDH1A1ALOX15HMGB1
Benzene SCHEMBL8597142 0.84 FOLH1 (0.59) FOLH1DPP4ALDH1A1ALOX15HMGB1
SCHEMBL4240167 0.83 HSD17B10 (0.51) FOLH1DPP4ALDH1A1HMGB1MAPK1
SCHEMBL12893382 0.83 DPP4 (0.48) FOLH1DPP4MYCALDH1A1KMT2A
SCHEMBL1919746 0.82 DPP4 (0.55) DPP4CYP2C9KDM4EHPGD
SCHEMBL7969105 0.82 FOLH1 (0.56) FOLH1MYCCYP3A4CYP2C9ALOX12
SCHEMBL7843765 0.82 FOLH1 (0.56) FOLH1MYCCYP3A4CYP2C9ALOX12
Hydrochloric Acid SCHEMBL4542361 0.82 FOLH1 (0.57) FOLH1DPP4ALDH1A1ALOX15HMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019011879-A1 THERAPEUTIC FOR TREATING CAPILLARY LEAK SYNDROME HENNING RAINER (CH) 2019-01-17 WO claimed
US-8088890-B2 Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2012-01-03 US claimed
EP-2328925-A1 PEPTIDES AND PEPTIDOMIMETIC COMPOUNDS, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION Fibrex Medical Research & Development GmbH (AT) 2011-06-08 EP claimed
EP-2274328-A1 PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION Fibrex Medical Research & Development GmbH (AT) 2011-01-19 EP claimed
WO-2010043444-A2 PHARMACEUTICAL PREPARATION FOR THE TREATMENT AND/OR PREVENTION OF ISCHEMIA/REPERFUSION INJURY AND THE SEQUELS THEREOF FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2010-04-22 WO claimed
WO-2010034041-A1 PEPTIDES AND PEPTIDOMIMETIC COMPOUNDS, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2010-04-01 WO claimed
US-20100081787-A1 PEPTIDES AND PEPTIDOMIMETIC COMPOUNDS, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2010-04-01 US claimed
WO-2009137850-A1 PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2009-11-19 WO claimed
EP-0683173-B1 Cyclic adhesion inhibitors MERCK PATENT GMBH (DE) 1999-08-11 EP claimed
US-5693612-A USED FOR PROPHYLAXIS AND TREATMENT OF DISORDERS OF THE CIRCULATION, BONES AND IN TUMOR THERAPY, AND AS ANTIMICROBIAL AND ANTIVIRAL ACTIVE COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-12-02 US claimed
JP-7304795-A None JP disclosed
EP-4153310-B1 BBETA-15-42 FOR THE TREATMENT OF VIRAL ENDOTHELITIS F4 PHARMA GMBH (AT) 2026-02-18 EP disclosed
EP-3830284-B1 BACTERIAL VAGINOSIS DIAGNOSTIC MOLOGIC LTD (GB) 2025-02-19 EP disclosed
US-20230293640-A1 COMPOUNDS FOR THE TREATMENT OF ENDOTHELIITIS IN CONTEXT OF VIRALLY CAUSED DISEASES F4 PHARMA GMBH (AT) 2023-09-21 US disclosed
CN-116348128-A Bβ15-42 for treating viral endopdermatitis F4医药有限责任公司 2023-06-27 CN disclosed
EP-0683173-A1 Cyclic adhesion inhibitors MERCK PATENT GmbH (DE) 1995-11-22 EP disclosed
JP-H07304795-A CYCLOPEPTIDE OF GENERAL FORMULA I MERCK PATENT GMBH 1995-11-21 JP disclosed
EP-0610439-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1994-08-17 EP disclosed
US-5234936-A Treating hypertension, congestive heart failure, hyperlipidemia and hypercholesterolemia AMERICAN HOME PRODUCTS CORPORATION (US) 1993-08-10 US disclosed
WO-1993008171-A1 PYRIMIDOCYCLOALKANES AS ANGIOTENSIN II ANTAGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293640-A1 COMPOUNDS FOR THE TREATMENT OF ENDOTHELIITIS IN CONTEXT OF VIRALLY CAUSED DISEASES FGB, SERPINC1, ECE1 FOLH1 776/4885DPP4 107/4885MYC 4123/4885
US-20100081787-A1 PEPTIDES AND PEPTIDOMIMETIC COMPOUNDS, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION NGLY1, GHRHR, GHSR FOLH1 3492/4885DPP4 3514/4885MYC 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.