Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.79 |
| ▸ | PGR | P06401 | 4/20 | 0.79 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008107 | 0.89 | NR3C1 (1.00) | NR3C1PGRSGK1APLNRBRD4 | |
| SCHEMBL2002007 | 0.79 | NR3C1 (0.82) | NR3C1PGRSGK1PIK3C3CASR | |
| SCHEMBL2006541 | 0.77 | NR3C1 (0.62) | NR3C1PGRSGK1APLNRS1PR1 | |
| SCHEMBL2006930 | 0.77 | NR3C1 (0.78) | NR3C1PGRS1PR1CASR | |
| SCHEMBL2008089 | 0.75 | NR3C1 (0.79) | NR3C1PGRSGK1S1PR1PIK3C3 | |
| SCHEMBL2004236 | 0.73 | NR3C1 (0.59) | NR3C1PGRBRD4 | |
| SCHEMBL2008086 | 0.69 | NR3C1 (0.78) | NR3C1PGRSGK1S1PR1PIK3C3 | |
| SCHEMBL5237877 | 0.68 | LRRK2 (0.49) | NR3C1PGR | |
| SCHEMBL2004688 | 0.68 | ALDH1A1 (0.47) | NR3C1PGRS1PR1 | |
| SCHEMBL17806608 | 0.67 | PRMT5 (0.45) | NR3C1PGRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |