SCHEMBL20074549

SCHEMBL20074549

CCCCCCCCCCCCCCCC(=O)NCCOC(=O)CCC(=O)OCCCOC(=O)CCC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.54
CASP2 P42575 1/20 0.53
FAAH O00519 4/20 0.53
L3MBTL1 Q9Y468 1/20 0.51
DNM1 Q05193 3/20 0.50
LPAR1 Q92633 2/20 0.49
LPAR2 Q9HBW0 2/20 0.49
ENPP2 Q13822 1/20 0.49
HTR2C P28335 1/20 0.49
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
NAAA Q02083 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21302767 0.95 DGKA (0.59) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL8922042 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL20856388 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL8921826 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL303966 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL8921681 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL8920345 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL8920199 0.91 DGKA (0.67) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL23177551 0.89 DGKA (0.56) DGKACASP2FAAHL3MBTL1DNM1
SCHEMBL23599342 0.89 CASP2 (0.64) DGKACASP2FAAHL3MBTL1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11547681-B2 N-acylethanolamide derivatives and uses thereof ELIEM THERAPEUTICS, INC. (US) 2023-01-10 US disclosed
US-20210093589-A1 N-ACYLETHANOLAMIDE DERIVATIVES AND USES THEREOF ELIEM THERAPEUTICS, INC. (US) 2021-04-01 US disclosed
WO-2018071679-A1 N-ACYLETHANOLAMIDE DERIVATIVES AND USES THEREOF CARNOT, LLC (US) 2018-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210093589-A1 N-ACYLETHANOLAMIDE DERIVATIVES AND USES THEREOF FAAH, FAAH2, NAAA DGKA 140/4885CASP2 3361/4885FAAH 1/4885
US-11547681-B2 N-acylethanolamide derivatives and uses thereof FAAH, FAAH2, NAAA DGKA 140/4885CASP2 3361/4885FAAH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.