SCHEMBL20076570

SCHEMBL20076570

C=C(C)c1cc(C)cc(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
RAPGEF4 Q8WZA2 1/20 0.35
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22306213 0.84 KDM4E (0.35) RAPGEF4
SCHEMBL22525816 0.82 TRPA1 (0.33)
SCHEMBL13980136 0.82 HDAC1 (0.36) SELLSELPSELE
SCHEMBL24629320 0.80 SELL (0.42) SELLSELPSELE
SCHEMBL20076889 0.78 IKBKE (0.33) CES2CES1
SCHEMBL23965650 0.77 CES2 (0.35) CES2CES1RAPGEF4SELLSELP
SCHEMBL8282394 0.76 CSNK2A1 (0.36) CES2CES1
SCHEMBL15177920 0.76 NFE2L2 (0.39) CES2CES1
SCHEMBL20076670 0.75 RAPGEF4 (0.32) CES2CES1RAPGEF4
SCHEMBL12621 0.74 RAPGEF4 (0.52) CES2CES1RAPGEF4SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed