Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076491 | 0.82 | KDM4E (0.37) | IKBKETBK1KDM4EMEN1KMT2A | |
| SCHEMBL20076570 | 0.78 | CES2 (0.35) | CES2CES1 | |
| SCHEMBL20076496 | 0.77 | TBK1 (0.30) | TBK1 | |
| SCHEMBL23864570 | 0.75 | ALDH1A1 (0.35) | IKBKETBK1CES2CES1KDM4E | |
| SCHEMBL10158627 | 0.75 | CRBN (0.38) | IKBKETBK1CES2CES1KDM4E | |
| SCHEMBL38657971 | 0.75 | CRBN (0.38) | IKBKETBK1CES2CES1KDM4E | |
| SCHEMBL671650 | 0.72 | KDM4E (0.48) | CES2CES1KDM4EMEN1KMT2A | |
| SCHEMBL30739727 | 0.72 | KDM4E (0.48) | CES2CES1KDM4EMEN1KMT2A | |
| SCHEMBL28058282 | 0.72 | CES2 (0.43) | CES2CES1KDM4EMEN1KMT2A | |
| SCHEMBL20076670 | 0.72 | RAPGEF4 (0.32) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |