Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137702 | 0.74 | — | — | |
| SCHEMBL865384 | 0.74 | — | — | |
| SCHEMBL767709 | 0.72 | — | — | |
| SCHEMBL865154 | 0.71 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16327 | 0.71 | TSHR (0.56) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8861475 | 0.69 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8861451 | 0.69 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL866991 | 0.69 | TSHR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5053935 | 0.69 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL6784539 | 0.69 | TSHR (0.53) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632873-B2 | Cosmetic dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | L'OREAL S.A. (FR) | 2009-12-15 | — | — | US | claimed |
| US-20050255068-A9 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | L'OREAL S.A. (FR) | 2005-11-17 | — | — | US | claimed |
| US-20040191199-A1 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | MOUGIN NATHALIE | 2004-09-30 | — | — | US | claimed |
| US-20040180019-A1 | Hair-cosmetic composition comprising at least one film-forming gradient copolymer, aerosol composition comprising the cosmetic composition and method for treating hair using the composition | L'OREAL S.A. (FR) | 2004-09-16 | — | — | US | claimed |
| EP-1444974-A2 | Hair care composition containing a filmbuilding copolmer with a gradient, aerosol composition and process for treating hair | L'OREAL (FR) | 2004-08-11 | — | — | EP | claimed |
| EP-1428495-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428496-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428493-A1 | Cosmetic or dermatological composition comprising a gradient copolymer and cosmetic process of make-up or care using this copolymer | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-7959906-B2 | Having specified strain at break, Young's modulus and/or instantaneous elastic recovery | L'OREAL S.A. (FR) | 2011-06-14 | — | — | US | disclosed |
| US-7632873-B2 | Cosmetic dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | L'OREAL S.A. (FR) | 2009-12-15 | — | — | US | disclosed |
| EP-1684870-B1 | USE OF A COMPOSITIONALLY-GRADED COPOLYMER IN AN AEROSOL DEVICE COMPRISING TWO COMPARTMENTS, AND AEROSOL DEVICE COMPRISING SAID COPOLYMER AND A COMPRESSED GAS | OREAL (FR) | 2008-01-02 | — | — | EP | disclosed |
| US-20070128127-A1 | Aerosol device containing a silicone, a gradient copolymer and a propellant essentially comprising dimethyl ether | L'OREAL (FR) | 2007-06-07 | — | — | US | disclosed |
| US-20070086959-A1 | Use of a compositionally gradient copolymer in an aerosol device comprising two compartments, and aerosol device comprising said copolymer and a compressed gas | L'OREAL (FR) | 2007-04-19 | — | — | US | disclosed |
| EP-1684870-A1 | USE OF A COMPOSITIONALLY-GRADED COPOLYMER IN AN AEROSOL DEVICE COMPRISING TWO COMPARTMENTS, AND AEROSOL DEVICE COMPRISING SAID COPOLYMER AND A COMPRESSED GAS | L'OREAL (FR) | 2006-08-02 | — | — | EP | disclosed |
| US-20040191199-A1 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | MOUGIN NATHALIE | 2004-09-30 | — | — | US | disclosed |
| US-20040180019-A1 | Hair-cosmetic composition comprising at least one film-forming gradient copolymer, aerosol composition comprising the cosmetic composition and method for treating hair using the composition | L'OREAL S.A. (FR) | 2004-09-16 | — | — | US | disclosed |
| EP-1444974-A2 | Hair care composition containing a filmbuilding copolmer with a gradient, aerosol composition and process for treating hair | L'OREAL (FR) | 2004-08-11 | — | — | EP | disclosed |
| EP-1428496-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1428495-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1428493-A1 | Cosmetic or dermatological composition comprising a gradient copolymer and cosmetic process of make-up or care using this copolymer | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040191199-A1 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | KRT18, POLR1C, CUTA | TSHR 2408/4885ALDH1A1 1429/4885TP53 1633/4885 |
| US-20070086959-A1 | Use of a compositionally gradient copolymer in an aerosol device comprising two compartments, and aerosol device comprising said copolymer and a compressed gas | POLR1C, PLOD2, KRT18 | TSHR 4734/4885ALDH1A1 2619/4885TP53 1416/4885 |
| US-20070128127-A1 | Aerosol device containing a silicone, a gradient copolymer and a propellant essentially comprising dimethyl ether | POLR1C, SHH, DPM1 | TSHR 2903/4885ALDH1A1 1948/4885TP53 2101/4885 |
| US-20050255068-A9 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | KRT18, POLR1C, CUTA | TSHR 2408/4885ALDH1A1 1429/4885TP53 1633/4885 |
| US-20040180019-A1 | Hair-cosmetic composition comprising at least one film-forming gradient copolymer, aerosol composition comprising the cosmetic composition and method for treating hair using the composition | POLR1C, PFN1, POLL | TSHR 832/4885ALDH1A1 1812/4885TP53 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.