Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179979 | 0.80 | CYP1A2 (0.44) | LMNATP53TRPM5KDM4EHSD17B10 | |
| SCHEMBL9979773 | 0.80 | CYP3A4 (0.49) | LMNATP53TRPM5KDM4EHSD17B10 | |
| SCHEMBL1068060 | 0.79 | LMNA (0.33) | LMNATP53TRPM5 | |
| SCHEMBL9976426 | 0.77 | LMNA (0.39) | LMNATP53TRPM5KDM4EHSD17B10 | |
| SCHEMBL22955088 | 0.77 | TRPM5 (0.39) | TRPM5KDM4ESYKBRD4 | |
| SCHEMBL9343342 | 0.77 | CNR1 (0.39) | TRPM5PDK2POLB | |
| SCHEMBL6184266 | 0.77 | TRPM5 (0.38) | TRPM5 | |
| SCHEMBL27304325 | 0.77 | TRPM5 (0.38) | TRPM5CA2BRD4 | |
| SCHEMBL3290937 | 0.76 | ALDH1A1 (0.44) | LMNATP53TRPM5KDM4EHSD17B10 | |
| SCHEMBL115421 | 0.76 | LMNA (0.40) | LMNATP53TRPM5KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751076-B1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | MEDIMMUNE LTD (GB) | 2018-04-25 | — | — | EP | disclosed |