Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979773 | 0.85 | CYP3A4 (0.49) | ALDH1A1LMNATP53TRPM5CHRNA7 | |
| SCHEMBL115421 | 0.85 | LMNA (0.40) | LMNATP53TRPM5CHRNA7CYP3A4 | |
| SCHEMBL9976426 | 0.83 | LMNA (0.39) | ALDH1A1LMNATP53TRPM5CHRNA7 | |
| SCHEMBL20079989 | 0.76 | LMNA (0.49) | LMNATP53TRPM5SYKKDM4E | |
| SCHEMBL1068060 | 0.76 | LMNA (0.33) | LMNATP53TRPM5CHRNA7 | |
| SCHEMBL13500632 | 0.75 | GAA (0.50) | ALDH1A1LMNAKDM4EHSD17B10KMT2A | |
| SCHEMBL27304325 | 0.74 | TRPM5 (0.38) | TRPM5CHRNA7CA2CA12CA3 | |
| SCHEMBL13500589 | 0.73 | NPC1 (0.49) | ALDH1A1LMNATP53SYKKDM4E | |
| SCHEMBL26548079 | 0.73 | TRPM5 (0.35) | TRPM5CHRNA7CYP3A4KMT2A | |
| SCHEMBL8914255 | 0.72 | TRPM5 (0.34) | LMNATP53TRPM5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |