Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007999 | 0.90 | GAA (0.44) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL2013251 | 0.88 | GAA (0.39) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL2014829 | 0.88 | L3MBTL1 (0.44) | KMT2AMEN1ITGB3ITGA2BL3MBTL1 | |
| SCHEMBL2012807 | 0.87 | NPC1 (0.44) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL2007940 | 0.87 | NPC1 (0.42) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL2011176 | 0.87 | ITGB3 (0.54) | KMT2AMEN1ITGB3ITGA2BL3MBTL1 | |
| SCHEMBL2010623 | 0.83 | MAPK1 (0.36) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL2012428 | 0.81 | HPGD (0.45) | KMT2AMEN1ALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL8836093 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL2011589 | 0.80 | CASP7 (0.40) | KMT2AMEN1ALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964628-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-06-21 | — | — | US | disclosed |
| US-20100256161-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-10-07 | — | — | US | disclosed |
| US-7759387-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256161-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | FGB, F13B, F2 | KMT2A 4561/4885MEN1 4472/4885ITGB3 169/4885 |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | FGB, F13B, F2 | KMT2A 4561/4885MEN1 4472/4885ITGB3 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.