Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980677 | 0.96 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL2008288 | 0.88 | ALDH1A1 (0.31) | ALDH1A1 | |
| Nitric Acid SCHEMBL7573471 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1650676 | 0.78 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL18870454 | 0.75 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL2918544 | 0.73 | — | — | |
| SCHEMBL6338975 | 0.72 | LMNA (0.40) | ALDH1A1 | |
| SCHEMBL11038404 | 0.71 | ALDH1A1 (0.50) | ALDH1A1 | |
| Butanol SCHEMBL8105837 | 0.70 | TSHR (0.59) | ALDH1A1 | |
| SCHEMBL3094284 | 0.70 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348073-A1 | Use of diamino-alcohol compouds in high solids mineral slurries | Dow Global Technologies LLC (US) | 2011-07-27 | — | — | EP | disclosed |
| EP-2341093-A1 | Novel diamino-alcohol compounds, their manufacture and use in epoxy resins | Dow Global Technologies LLC (US) | 2011-07-06 | — | — | EP | disclosed |
| EP-2338941-A1 | Novel diamino-alcohol compounds, their manufacture and use in coatings applications | Dow Global Technologies LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| EP-2338872-A2 | Diamino-alcohol compounds and processes for their manufacture | Dow Global Technologies LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| US-20110147649-A1 | Novel diamino-alcohol compounds, their manufacture and use in high solids mineral slurries | ADVANCION CORPORATION | 2011-06-23 | — | — | US | disclosed |
| US-20110152574-A1 | Novel diamino-alcohol compounds and processes for their manufacture | ADVANCION CORPORATION | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152574-A1 | Novel diamino-alcohol compounds and processes for their manufacture | ADH1A, ADH1C, ADH5 | ALDH1A1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.