SCHEMBL2008360

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4437839	0.93	CYP11B2 (0.35)	NR3C1CYP11B2CYP11B1GRM1CYP17A1
	SCHEMBL4447721	0.89	MAPT (0.35)	NR3C1CYP11B2CYP11B1GRM1CYP17A1
	SCHEMBL2006894	0.86	NR3C1 (0.38)	NR3C1CYP11B2CYP11B1CYP17A1CYP1A2
	SCHEMBL2003406	0.83	CYP11B1 (0.38)	NR3C1CYP11B2CYP11B1GRM1CYP17A1
	SCHEMBL2005767	0.83	ESRRA (0.36)	NR3C1CYP11B2CYP11B1GRM1ESR1
	SCHEMBL2004925	0.83	ESR1 (0.37)	NR3C1CYP11B2CYP11B1ESR1ESR2
	SCHEMBL2002221	0.80	PGR (0.40)	NR3C1CYP11B2ESR1ESR2PGR
	SCHEMBL12572492	0.80	ESR1 (0.33)	NR3C1CYP11B2CYP11B1ESR1ESR2
	SCHEMBL2006268	0.80	TRPA1 (0.35)	NR3C1CYP11B2CYP11B1CCR1ESR1
	SCHEMBL2009185	0.80	CYP11B1 (0.39)	NR3C1CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.