Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.53 |
| ▸ | UBE2M | P61081 | 2/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844912 | 0.83 | MCHR1 (0.42) | MCHR1 | |
| SCHEMBL20083976 | 0.82 | ACKR3 (0.49) | — | |
| SCHEMBL20083992 | 0.82 | POLB (0.43) | LMNATP53KDR | |
| SCHEMBL21844836 | 0.81 | ACKR3 (0.51) | — | |
| SCHEMBL20083898 | 0.80 | KDR (0.44) | KDR | |
| SCHEMBL21844832 | 0.79 | ACKR3 (0.50) | TP53MAPT | |
| SCHEMBL19157145 | 0.79 | POLB (0.42) | KDR | |
| SCHEMBL21844944 | 0.79 | HTR1A (0.54) | UBE2MDCUN1D1TP53MAPT | |
| SCHEMBL20083978 | 0.78 | ACKR3 (0.43) | TP53MAPT | |
| SCHEMBL19157226 | 0.78 | HTR1A (0.41) | TP53KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |