Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083992 | 0.89 | POLB (0.43) | ACKR3POLBHTR1AHTR1DHTR1B | |
| SCHEMBL21844836 | 0.89 | ACKR3 (0.51) | ACKR3PARP1HTR2BHTR1AHTR1D | |
| SCHEMBL21844832 | 0.87 | ACKR3 (0.50) | ACKR3POLBHTR1AHTR1DHTR1B | |
| SCHEMBL19157145 | 0.87 | POLB (0.42) | ACKR3POLBHTR1AHTR1DHTR1B | |
| SCHEMBL20083978 | 0.86 | ACKR3 (0.43) | ACKR3HTR1AHTR1DHTR1BROCK2 | |
| SCHEMBL19157261 | 0.82 | ACKR3 (0.49) | ACKR3PARP1HTR2BHTR1AHTR1D | |
| SCHEMBL20083956 | 0.82 | MCHR1 (0.53) | — | |
| SCHEMBL21844912 | 0.80 | MCHR1 (0.42) | ACKR3ROCK2 | |
| SCHEMBL19157709 | 0.80 | RAB9A (0.49) | ACKR3KMT2AKCNH2 | |
| SCHEMBL19157071 | 0.79 | ROCK2 (0.49) | ACKR3HTR1AROCK2DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |