Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083898 | 0.84 | KDR (0.44) | ROCK2ACKR3 | |
| SCHEMBL20083956 | 0.83 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL19157226 | 0.82 | HTR1A (0.41) | ACKR3 | |
| SCHEMBL21844911 | 0.81 | TERT (0.44) | MCHR1ROCK2HRH3ACKR3 | |
| SCHEMBL20083976 | 0.80 | ACKR3 (0.49) | ROCK2ACKR3 | |
| SCHEMBL20083992 | 0.80 | POLB (0.43) | ROCK2ACKR3 | |
| SCHEMBL15280073 | 0.79 | KMT2A (0.51) | — | |
| SCHEMBL21844836 | 0.79 | ACKR3 (0.51) | ACKR3 | |
| SCHEMBL21844832 | 0.77 | ACKR3 (0.50) | ROCK2ACKR3 | |
| SCHEMBL19157145 | 0.77 | POLB (0.42) | ROCK2ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |