Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157709 | 0.91 | RAB9A (0.49) | GAAHTTRAB9AACKR3TP53 | |
| SCHEMBL20083976 | 0.89 | ACKR3 (0.49) | POLBROCK2ACKR3HTR1AHTR1D | |
| SCHEMBL21844832 | 0.87 | ACKR3 (0.50) | POLBRAB9AROCK2ACKR3HTR1A | |
| SCHEMBL19157145 | 0.87 | POLB (0.42) | POLBGAAHTTRAB9AROCK2 | |
| SCHEMBL20083978 | 0.86 | ACKR3 (0.43) | GAAHTTRAB9AROCK2ACKR3 | |
| SCHEMBL20083956 | 0.82 | MCHR1 (0.53) | KDRLMNATP53 | |
| SCHEMBL21844912 | 0.80 | MCHR1 (0.42) | ROCK2ACKR3 | |
| SCHEMBL19157071 | 0.79 | ROCK2 (0.49) | ROCK2ACKR3HTR1ASPHK2SPHK1 | |
| SCHEMBL19157226 | 0.78 | HTR1A (0.41) | RAB9AACKR3KDRHTR1AHTR1D | |
| SCHEMBL21844836 | 0.77 | ACKR3 (0.51) | ACKR3HTR1AHTR1DHTR1BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |