Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844909 | 0.85 | KMT2A (0.40) | MAOBACKR3RAB9ANPC1KDM1A | |
| SCHEMBL20084043 | 0.83 | SMN1; SMN2 (0.47) | ACKR3RAB9ANPC1LMNAMAPT | |
| SCHEMBL21844908 | 0.83 | KDM1A (0.48) | RAB9ANPC1KDM1ALMNAMAPT | |
| SCHEMBL15276908 | 0.78 | ALDH1A1 (0.44) | MAOBMGLLRAB9ANPC1LMNA | |
| SCHEMBL19157637 | 0.77 | NPC1 (0.50) | MAOBACKR3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15276895 | 0.71 | LMNA (0.53) | RAB9ANPC1LMNAGAAMAPT | |
| SCHEMBL15276909 | 0.70 | RAB9A (0.50) | RAB9ANPC1LMNAGAAMAPT | |
| SCHEMBL30456589 | 0.70 | NPC1 (0.77) | MAOBRAB9ANPC1KCNQ3KCNQ2 | |
| SCHEMBL7969220 | 0.70 | NPC1 (0.61) | MAOBRAB9ANPC1LMNAMAPT | |
| SCHEMBL19156955 | 0.69 | KCNK3 (0.66) | MAOBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |