Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20088936 | 1.00 | TSHR (0.35) | TSHRGAPDHTRPA1PAX8PTPN1 | |
| SCHEMBL18160120 | 1.00 | TSHR (0.35) | TSHRGAPDHTRPA1PAX8PTPN1 | |
| SCHEMBL5494816 | 0.84 | TSHR (0.33) | TSHRGAPDHTRPA1 | |
| SCHEMBL5499760 | 0.84 | TSHR (0.33) | TSHRGAPDHTRPA1 | |
| SCHEMBL13176735 | 0.84 | TSHR (0.33) | TSHRGAPDHTRPA1PAX8 | |
| SCHEMBL5840288 | 0.82 | — | — | |
| SCHEMBL1189342 | 0.82 | — | — | |
| SCHEMBL8890971 | 0.82 | — | — | |
| SCHEMBL4014096 | 0.82 | — | — | |
| SCHEMBL18160108 | 0.81 | LMNA (0.52) | TSHRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180110871-A1 | DUAL DISULFIDE DRUG CONJUGATES | ENDOCYTE INC (US) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110871-A1 | DUAL DISULFIDE DRUG CONJUGATES | DHFR, DUOX2, DUOX1 | TSHR 274/4885GAPDH 2286/4885TRPA1 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.