SCHEMBL20090174

SCHEMBL20090174

O=P(c1ccccc1)(c1ccc2ccccc2c1)c1ccc2c(ccc3cc(-c4ccc5c(c4)c4c6ccccc6ccc4c4nc6ccc(-c7cccc8ccccc78)cc6n54)ccc32)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.33
CAMKK1 Q8N5S9 2/20 0.32
CAMKK2 Q96RR4 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
KMT2A Q03164 1/20 0.32
FLT3 P36888 1/20 0.31
PPARG P37231 2/20 0.31
PPARA Q07869 2/20 0.31
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
PIM3 Q86V86 1/20 0.30
DYRK2 Q92630 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20090155 0.98 AHR (0.34) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL20090159 0.94 AHR (0.36) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL20090181 0.90 MET (0.33) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL20090166 0.89 AHR (0.32) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL19960276 0.89 ALDH1A1 (0.36) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL19960260 0.88 AHR (0.34) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL19960336 0.88 AHR (0.36) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL19960328 0.88 AHR (0.36) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL20090162 0.87 AHR (0.34) AHRCAMKK1CAMKK2CYP2C9CYP2C19
SCHEMBL20090132 0.87 KMT2A (0.40) AHRCAMKK1CAMKK2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2019-07-16 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 AHR 58/4885CAMKK1 4412/4885CAMKK2 3981/4885
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 AHR 58/4885CAMKK1 4412/4885CAMKK2 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.