SCHEMBL20090175

SCHEMBL20090175

O=P(c1ccccc1)(c1ccccc1)c1ncc(-c2ccc3c(c2)c2ccc4ccccc4c2c2nc4ccc(-c5cccc6ccccc56)cc4n32)c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MCL1 Q07820 1/20 0.30
ACMSD Q8TDX5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20090243 0.93 AHR (0.33) PTGESCA12CA9MCL1ACMSD
SCHEMBL20090173 0.91 PTGES (0.30) PTGES
SCHEMBL20090244 0.84 AHR (0.32)
SCHEMBL20090159 0.82 AHR (0.36) PTGESCA12CA9KDM4EALDH1A1
SCHEMBL20090239 0.80 PTGES (0.33) PTGESKDM4EALDH1A1
SCHEMBL20090171 0.80 PTGES (0.31) PTGES
SCHEMBL19929016 0.79 ALDH1A1 (0.36) PTGESKDM4EALDH1A1
SCHEMBL20090155 0.79 AHR (0.34) PTGESCA12CA9MCL1ACMSD
SCHEMBL19929898 0.78 PTGES (0.34) PTGES
SCHEMBL20090187 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2019-07-16 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180114923-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, PER2 PTGES 1252/4885CA12 1530/4885CA9 1460/4885
US-10355225-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 PTGES 1252/4885CA12 1530/4885CA9 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.